Extended Data Fig. 3: Ability of A3E and CPM to inhibit minimally laboratory-experienced RSV.
From: A condensate-hardening drug blocks RSV replication in vivo
a, Inhibition of minimally laboratory-experienced RSV was tested in HEp-2 cells infected for 24 h with two RSV A or one RSV B isolates and analysed by flow cytometry as described in the Methods. The results are expressed as mean ± s.d. from three independent experiments performed in duplicate. b, c, IC50 values are calculated from three independent experiments performed in duplicate. CC50 values are from a representative experiment out of three experiments performed in triplicate. The selectivity index (SI) is calculated as SI = CC50/IC50.
