Extended Data Fig. 5: Marker gene expression and site-specific codon abundance over the cell cycle. | Nature

Extended Data Fig. 5: Marker gene expression and site-specific codon abundance over the cell cycle.

From: Single-cell Ribo-seq reveals cell cycle-dependent translational pausing

Extended Data Fig. 5

a, Heat map of RPF abundance per CDS in hTERT RPE-1 FUCCI cells, showing the translation dynamics of 1,853 significantly differentially translated genes during the cell cycle. Common cell cycle markers are highlighted. b, Heat map showing ribosome-site-specific pausing over all codons for hTERT RPE-1 FUCCI cells. Cells are ordered based on cell cycle progression, and codons are clustered based on the average change in the frequency of occurrence across all sites. Codons with significantly different site occupancies between clusters are indicated with an asterisk.

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