Extended Data Fig. 7: Bacterial aggregation of mIgA-4308.
From: Parallelism of intestinal secretory IgA shapes functional microbial fitness
a, OD of E. coli JM83 grown in the presence of mIgA (\(\bar{x}\) ± s.d., n = 4 for each condition, mIgA4308 P = 0.0054). b, c, Bacterial aggregates of fim-locked E. coli strain AAEC189[pSH2]33 after addition of mIgA or yeast mannan quantified (b) and as representative images (c). Box plot shows mean and 25–75th percentiles, whiskers show minimum and maximum value (b). mSIgA4308 n = 68, mSIgAB8-030 n = 70, Mannan n = 58 and mSIgA4250 n = 68. Bar corresponds to 10 μm. Statistics show two-sided paired t-test (a) and two-sided unpaired t-test (b). Data are representative from three experiments (c) or pooled from two (a) or three (b) independent experiments.
