Extended Data Fig. 8: Comparison of signaling during mesoderm formation in the human and mouse. | Nature

Extended Data Fig. 8: Comparison of signaling during mesoderm formation in the human and mouse.

From: Single-cell transcriptomic characterization of a gastrulating human embryo

Extended Data Fig. 8: Comparison of signaling during mesoderm formation in the human and mouse.The alternative text for this image may have been generated using AI.

Heatmap comparison of the z-score-normalized log expression values of components of FGF, TGF-β and Wnt signaling pathways in the human gastrula, mouse embryos (E7.25 stage) and cultured cynomolgus macaque embryos (16 d.p.f stage). From human and mouse we considered the Epiblast (Epi), Primitive Streak (PS) and Nascent Mesoderm (NM) clusters; in the macaque, we used the clusters annotated as postL-Epi, L-Gast1 and L-Gast2.

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