Extended Data Fig. 4: Rostral and Caudal differences in diversification of mesodermal subtypes.
From: Single-cell transcriptomic characterization of a gastrulating human embryo
a, UMAP highlighting combinatorial gene expression. Individual gene expression (left) is reported as the log expression whilst combinatorial plots (right) show scaled log expression values. b, Diffusion map of cells from the 6 mesoderm related clusters (Primitive Streak, PS; Nascent Mesoderm, NM; Emergent Mesoderm, EM; Mesoderm, Meso; Axial Mesoderm, AxM; Extraembryonic Mesoderm, ExM), with the first and the second diffusion components plotted. c, Diffusion map of mesodermal showing the log expression levels of mesodermal markers genes. d, Differential gene expression between rostral and caudal advanced mesoderm cells. Significantly upregulated in rostral (*) or caudal (#) cells. e-j, Diffusion map of mesodermal clusters showing log expression levels of mesoderm subtype markers.
