Extended Data Fig. 5: Pfsa+ allele frequency and sample size by year of ascertainment.
From: Malaria protection due to sickle haemoglobin depends on parasite genotype
a) points show the sample allele frequency (y axis) for each Pfsa variant (rows) in severe malaria cases by year of ascertainment (x axis) and country (colour). Vertical line segments show the 95% confidence interval corresponding to each estimate. Horizontal dashed lines show the overall estimate across all years in our data, as in Fig. 3a. b) Bars show the total number of severe case samples in our dataset (y axis) in each country (colour) by year of ascertainment (x axis).
