Extended Data Fig. 5: Domain architecture of TokK.
From: Structure of a B12-dependent radical SAM enzyme in carbapenem biosynthesis
a, The three domains of TokK are portrayed in a ribbon diagram. The N-terminal Cbl-binding domain is shown in teal, the RS domain is shown in light blue, and the C-terminal domain is shown in pink. b, A topology diagram of TokK with domains coloured as in a. The Cbl is portrayed in sticks, and the lower axial Trp side chain is shown as a red dot. The iron-sulfur cluster is shown in orange and yellow spheres, and the ligating Cys residues are shown as small yellow spheres. c–e, Zoomed in views of the C-terminal domain (c), RS domain (d) and Cbl-binding domain (e) are shown as ribbon diagrams.
