Fig. 3: Genetic and functional insights into atrial fibrillation.
From: Genetic associations of protein-coding variants in human disease
Clustered Mendelian randomization plot of association of atrial fibrillation loci with pulse rate. Only variants with cluster inclusion probability greater than 0.7 are included. Top left, CWAS loci (sentinels). Top right, overlapping CWAS and atrial fibrillation GWAS loci. Bottom left, all atrial fibrillation GWAS loci from Nielsen et al.49 (with zoomed inset). Bottom right, all atrial fibrillation GWAS loci with permuted pulse (null, with zoomed inset).
