Fig. 4: cfRNA measurements reflect the multifactorial nature and pathogenesis of preeclampsia over pregnancy before diagnosis.
From: Early prediction of preeclampsia in pregnancy with cell-free RNA
a, DEGs for preeclampsia with as compared to without severe features (n = 503) can be described by four longitudinal trends. b, Comparison of organ and cell-type changes over gestation for eight organ systems reflects the multifactorial nature of preeclampsia and provides a possible means to comprehensively monitor maternal organ health. Points indicate median per sample group and shaded region indicates 95% CI in a and 75% CI in b. LSECs, liver sinusoidal endothelial cells; NK cells, natural killer cells.
