Extended Data Fig. 3: Across gestation and before diagnosis, changes in the cfRNA transcriptome identified at one time point can moderately segregate preeclampsia and normotensive samples at other time points.
From: Early prediction of preeclampsia in pregnancy with cell-free RNA
DEGs with |log2(FC)| ≥ 1 and CV < 0.5 or 0.4 for the 13–20 week time point were identified at each time point across gestation. Each row visualizes how well a specific DEG subset from a given sample collection period can separate preeclampsia (n = 13, 16, 20, 17) and normotensive (n = 36, 33, 37, 29) samples in all other collection periods (≤12, 13–20, ≥23 weeks of gestation and post-partum respectively). The number of genes identified per sample collection period is highlighted along the main diagonal.
