Extended Data Table 2 Overview of results for data-driven analysis of mass cytometry data using diffcyt

From: Twin study reveals non-heritable immune perturbations in multiple sclerosis

  1. Shown are cluster-marker combinations that were statistically significant (p adj < 0.05) in two comparisons: 1) comparing all MS-affected twins to their unaffected twin siblings and 2) comparing only untreated MS-affected twins to unaffected siblings using the moderated limma-trend method implemented in diffcyt with a false-discovery correction according to the Benjamini-Hochberg approach.
  2. Tna = naive T cells; Temra = effector memory T cells re-expressing CD45RA.