Extended Data Fig. 2: Growth of Omicron, Delta and B.1.1 in different cells. | Nature

Extended Data Fig. 2: Growth of Omicron, Delta and B.1.1 in different cells.

From: Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant

Extended Data Fig. 2

A D614G-bearing B.1.1 virus, Delta and Omicron [100 TCID50 (m.o.i. = 0.01) for VeroE6/TMPRSS2 cells, 1,000 TCID50 (m.o.i. = 0.1) for HeLa-ACE2/TMPRSS2 cells and A549 cells] were inoculated into cells, and the viral RNA copy number in the supernatant was quantified by RT–qPCR. Assays were performed in quadruplicate. Data are mean ± s.d. In the data of VeroE6/TMPRSS2 cells (left) and HeLa-ACE2/TMPRSS2 cells (middle), statistically significant differences versus B.1.1 and Delta through time points were determined by multiple regression. FWERs calculated using the Holm method are indicated in the figures.

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