Extended Data Fig. 1: Relative abundance of intestinal fungal genera in non-IBD and patients with UC.
From: Immune regulation by fungal strain diversity in inflammatory bowel disease
a, Alpha diversity analysis was analysed using the Shannon diversity index among fungi communities at the fungal OTU level in colonic mucosa (MUC) enriched samples from non-IBD or ulcerative colitis-affected (UC) individuals. Based on quality control one non-IBD sample was excluded from further mycobiome sequencing and analysis. b, Non-metric multidimensional scaling (NMDS) plot of distance ordination based on Bray–Curtis dissimilarities for fungal ITS1 OTUs in colonic mucosa (MUC) enriched samples from non-IBD or ulcerative colitis-affected (UC) individuals. Analysis of similarities (ANOSIM) statistics. c, Relative genus abundance of intestinal fungal genera. Boxplots in a and c, the lower and upper hinges correspond to the first and third quartiles (the 25th and 75th percentiles). The horizontal line shows the median. a–c, Each dot represents an individual human subject, non-IBD (n = 37) or ulcerative colitis-affected (UC, n = 40) individuals. Analysis performed with two-sided, non-paired, Mann-Whitney test, Benjamini-Hochberg (BH) corrected for data in a and c.
