Extended Data Fig. 8: Zonation in human brain mural cells.

a. Indirect immunofluorescence of SLC30A10 expression in human and mouse brain cortex. b. Indirect immunofluorescence of GRM8 expression in human and mouse brain cortex. c. Indirect immunofluorescence of FRMD3 expression in human and mouse brain cortex. d. Indirect immunofluorescence localization of FRMD3 on ACTA2+ (known SMC marker) vessels. e. Enriched Gene Ontology terms in mural zones. Representative images in a–d from n = 3 independent biological replicates for each marker. Brightness and contrast enhanced for visualization. Scale bar, 20 μm.