Extended Data Fig. 2: Evaluation of cryo-EM reconstructions.
From: Structure of active human telomerase with telomere shelterin protein TPP1
a, Plot of the Fourier shell correlation (FSC) as a function of the spatial frequency of the final reconstructions. b, c, Local resolution evaluation of the H/ACA RNP (b) and catalytic core (c) reconstructions. d, e, Euler angle distribution of sub-particles used for the H/ACA RNP (d) and catalytic core (e) reconstructions. f, FSC coefficients as a function of spatial frequency between model and corresponding cryo-EM density maps. g–j, Representative cryo-EM densities encasing the corresponding atomic models of H/ACA proteins (g), TERT (h), TER (i) and the four base pairs in the template–DNA duplex (j).
