Fig. 1: BA.2 exhibits a similar serum neutralization profile to those of BA.1 sublineages.
From: Antibody evasion properties of SARS-CoV-2 Omicron sublineages
a, Proportions of BA.1, BA.1+R346K and BA.2 in B.1.1.529 sequences on GISAID over the latter half of December 2021 and January 2022. The value in the upper right corner of each box denotes the cumulative number of Omicron sequences. b, Alterations in the B.1.1.529 lineage. NTD, N-terminal domain; RBD, receptor-binding domain; SD1, subdomain 1; SD2, subdomain 2; FP, fusion peptide; HR1, heptad repeat 1; CH, central helix; CD, connector domain; HR2, heptad repeat 2; CT, cytoplasmic tail. c, Pseudovirus neutralization by convalescent and vaccinee sera. n = 10, 12, 13 and 15 biologically independent serum samples, respectively, for convalescent, mRNA-1273, BNT162b2 and boosted groups. The values above the points indicate geometric means. The numbers in parentheses denote the numbers of samples above the limit of detection (LOD) of 100. Values below the LOD are arbitrarily plotted to allow for visualization of each sample. P values were determined by a two-sided Friedman test followed by Dunn’s multiple comparisons test.
