Extended Data Fig. 6: NTCP amino acid conservation surface mapping.
From: Structural basis of sodium-dependent bile salt uptake into the liver
Amino acid conservation across NTCP vertebrate orthologs is mapped into NTCPEM inward-facing (left) and open-pore (right) structures. Spheres represent alpha-carbon atoms of 7 consensus mutations to improve thermal stability in the construct used for cryo-EM analysis (NTCPEM).
