Extended Data Fig. 3: Multiple sequence alignments of the central linker regions. | Nature

Extended Data Fig. 3: Multiple sequence alignments of the central linker regions.

From: Structure of the Dicer-2–R2D2 heterodimer bound to a small RNA duplex

Extended Data Fig. 3

(a, b) Multiple sequence alignments of the central linker regions in Dicer-2, Dicer-1, and human Dicer (a), and the Dicer-2 orthologs from insect species (b). The secondary structure of Dicer-2 is indicated above the sequences. The connector helix, the central linker, and the RNase III domain are highlighted in pink, beige, and light green, respectively. The key residues are marked by triangles.

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