Fig. 1: Structures of pre-SSU-1 and pre-SSU-2 states.
From: Mechanism of mitoribosomal small subunit biogenesis and preinitiation
a, Pre-SSU-1 with RBFA and TFB1M. Unfolded rRNA is in orange. RBFA-CTE (surface model) blocking the mRNA channel (upper left), TFB1M binding (bottom left), and superposition of pre-SSU-1 with mature SSU showing clashes of RBFA with mS37 (right) are displayed. b, Superposition of pre-SSU-1 with mature SSU rRNA shows an upwards displacement of h28 due to extended association with RFBA that also interacts with the rRNA 3′ end. c, Pre-SSU-2 with RBFA. d, Comparison of pre-SSU-1 and pre-SSU-2 shows that the mS38 N-terminal helix is disordered in pre-SSU-1. aa, amino acid; NTE, N-terminal extension.
