Extended Data Fig. 11: Caspase-7 enhances ceramide production through ASM after NK–CTL attack.
From: Caspase-7 activates ASM to repair gasdermin and perforin pores
a–c, Mice were treated with IMP or PBS, followed by intraperitoneal infection with 104 C. violaceum and collected at 3 dpi. Representative images of infected livers from WT (a), Casp7–/– (b), or WT+IMP (c) mice stained for nuclei (DAPI; blue), cleaved caspase-7 (white), and ceramide (red). Scale bars, 50 μm. Data are representative of 3 experiments.
