Extended Data Fig. 8: Similar weights, morphology, and organ histology of C11orf53+/+ and C11orf53−/− mice. WT: C11orf53+/+ mice, KO: C11orf53−/− mice.
From: OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage
(a) Body weights of C11orf53 F2 mice of each genotype (2 female WT mice, 4 male WT mice; 3 female KO mice, 4 male KO mice; 5 HET male and female mice were included in the experiment with 6–10 weeks old littermate mice). (b) Representative images of C11orf53+/+ and C11orf53−/− mice F2 mice (representative image of four mice). (c) H&E analysis of representative organs from age- and sex-matched C11orf53+/+ and C11orf53−/− littermate mice (one female and one male mice for both genotypes were included in the experiment). All scale bars represent 200 μm. Source data for mice body weight is provided in Supplementary Table 5.
