Fig. 4: Goal-centred firing by ConSink cells is reduced on error subtrials.
From: Hippocampal place cells have goal-oriented vector fields during navigation
a, Example ConSink cell (rat 2, cell TT18c1, trial 16) immediately before a correct choice. Note the side-to-side scanning and robust firing in the goalward direction before the move onto the correct platform (goal beyond the top of the frame). b, Same cell as in a before an incorrect choice. c, Firing rates in the goalward direction were reduced on error trials, during both wait period 1 (the 4-s period before raising the choice platforms; top) and wait period 2 (the 4-s period before movement onto the chosen platform; bottom). Wilcoxson signed-rank test, two sided: n = 142 cells from five rats, z = 5.61, P = 1.97 × 10−8 (wait period 1); z = 4.87, P = 1.14 × 10−6 (wait period 2). d, Fantail plots of firing rates in directions relative to goal during correct choices have canonical forms, as in Fig. 3k, and peaks much closer to 0º than during incorrect choices. e, The tuning of ConSink cells to their individual sink positions is also disrupted on incorrect choices. Wilcoxson signed-rank test, one sided: n = 142 cells from five rats, z = 3.27, P = 5.46 × 10−4 (wait period 1); z = 3.88, P = 5.17 × 10−5 (wait period 2). For box plots in c and e, the central mark indicates the median and the bottom and top edges of the box indicate the 25th and 75th percentiles, respectively; the whiskers extend to the most extreme data points within 1.5 times the interquartile range from the bottom or top of the box, and all more extreme points are plotted individually using a plus symbol. **P < 0.001.
