Extended Data Fig. 10: Allele specific analysis on all GTEx samples.
From: Transcriptome variation in human tissues revealed by long-read sequencing
A) Estimated power for different number of transcripts (2, 3 or 5) with respect to the coverage (x-axis) for effect sizes 0.1 (low), 0.3 (medium) and 0.5 (high), derived from simulated count data. B) Number of genes tested for allele-specific expression (ASE) and allele-specific transcript structure (ASTS) and number of significant genes. The diagonal indicates the median percentage of significant genes (9% and 9%, respectively). C) Number of transcripts per gene tested for ASTS. D) Number of genes with allelic data across donors per tissue for ASE and ASTS. E) Total number of genes calculated per sample (n = 59) at different levels of power. Outliers are hidden for ease of viewing. The center corresponds to the median, the lower and upper hinges correspond to the 25th and 75th percentiles and the whiskers extend from the hinge to the smallest/largest value no further than 1.5 * inter-quartile range from the hinge.
