Extended Data Fig. 6: NAGK does not impact on MTP uptake.
From: Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation
a and b, Top left schematic representation of the Fluorescein labelled molecules. Bar charts and histograms represent flow cytometry analysis of KBM-7-IL1BmScarlet WT (grey) and NAGKKO pool (dark blue) cells treated with either MTP-Fluorescein (a) or lac-TP-Fluorescein (b) for indicated time periods, MFI represents median fluorescence intensity. Bar chart represents the mean ± s.e.m of n = 3 independent biological samples; two-way ANOVA with Šídák’s multiple comparisons test. Histograms represent one experiment shown of three independent experiments. The same untreated samples were used for the MTP-Fluorescein and lac-TP-Fluorescein uptake experiments as controls. **** p < 0.0001 or as indicated.
