Extended Data Fig. 3: NAGK does not impact on other NF-kB activating immune pathways.
From: Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation
Flow cytometry analysis of KBM-7-IL1BmScarlet WT (grey) and NAGKKO pool (dark blue) cells treated with the indicated increasing doses of Pam3CSK4, PMA, recombinant IL-1β, and TNF for 16 h. Mean ± s.e.m of n = 3 independent biological samples; two-way ANOVA with Šídák’s multiple comparisons test. **** p < 0.0001 or as indicated.
