Extended Data Fig. 4: NTS responses to intestinal stimuli.

a, Heat maps depicting the time-resolved responses of all responding NTS neurons to various magnitudes of duodenum stretch (top, 271 neurons) and jejunum stretch (bottom, 118 neurons), 6 mice, white bar: 10 seconds. b, Peak ΔF/F of neurons in a that responded to stimuli indicated, F test for non-zero slope: ****P < 0.0001. c, Heat map depicting the time-resolved responses of all 74 responding NTS neurons (2 mice) to duodenal perfusion (24 s) of glucose (300 mM in HBSS, purple) and saline (HBSS, olive), scale bar: 10 s. d, Heat map depicting the time-resolved responses of all 492 responding NTS neurons (2 mice) to duodenal perfusion of glucose (300 mM, dark purple), duodenum stretch (red: 140 μl), and stomach stretch (600 μl, green), white bar: 10 s.