Extended Data Fig. 3: Cryo-EM maps, cryo-EM images and resolution estimates.
From: Structures of α-synuclein filaments from human brains with Lewy pathology
(a), α-Synuclein filaments (blue arrows) from PDD1. Scale bars, 50 nm. (b), Projection features of Lewy filament. Scale bars, 5 nm. (c), Zoomed-in view of the main chain showing density of the oxygen atoms. (d), Fourier shell correlation (FSC) curves for cryo-EM maps are shown in black; for the final refined atomic model against the final cryo-EM map in red; for the atomic model refined in the first half map against that half map in blue; for the refined atomic model in the first half map against the other half map in yellow. (e), Side view of α-synuclein filaments with the Lewy fold.
