Extended Data Fig. 8: Frequencies of identified 3CLpro mutations in GISAID.
From: Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir

a, All occurrences of the indicated mutations were tabulated from GISAID. b, All occurrences of the indicated mutations were tabulated from GISAID in the three months prior to EUA (9/22/2021 to 12/22/2021) or after EUA (3/26/2022 to 6/26/2022).