Extended Data Fig. 3: Mutations studied as isogenic recombinant SARS-CoV-2 overlaid onto the 3CL protease structure.
From: Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir
The Cα of each residue that was mutated is denoted with a red sphere. The 3CLpro-nirmatrelvir complex was downloaded from PDB under accession code 7VH8.
