Extended Data Fig. 6: The transcriptomic comparison of three germ layers between monkey and mouse.

a–c, Heatmaps showing the DEGs in indicated monkey (Mk) and mouse (Ms) cell types related with ectoderm (a), mesoderm (b) and endoderm (c) development. Color bars, normalized expression level of different genes from high (red) to low (blue) in indicated cell types. d–f, Heatmaps of the correlation coefficients among the indicated cells including those reported by mouse dataset based on the cynomolgus monkey ontogenic gene levels, performed by Pearson Correlation Coefficient. Gene expression values of the integrated dataset were calculated by “cor()” in R, here and after. No other statistical analysis. Colors from blue to red indicate the low to high levels of Pearson Correlation Coefficient between each cell types, here and after.