Extended Data Fig. 1: IR exposure of hermaphrodite WT in the late L4 stage leads to extended transgenerational embryonic lethality.
From: Inheritance of paternal DNA damage by histone-mediated repair restriction
a. Transgenerational lethality characterization for IR treated WT hermaphrodites at the L3 (start of spermatogenesis), young L4 (ongoing spermatogenesis) and late L4 stage (mature sperm is stored in the spermatheca). Ten worms were included for each biological replicate, and n = 3 biological replicates. Error bars indicate median with 95% CI. b. Progeny lethality characterization for multiple generations upon IR treatment at the late L4 stage of hermaphrodites P0. Ten worms for each dosage group were included for each biological replicate, and n = 3 biological replicates. Error bars indicate median with 95% CI.
