Extended Data Fig. 3: The CalpL/cA4 complex.
From: Antiviral signalling by a cyclic nucleotide activated CRISPR protease
a, Close-up of cA4 (green) bound to the SAVED domain of CalpL. The blue mesh is a 2mFo-DFc electron density map contoured at 1.0 σ. b, Superposition of CalpL apo (white) onto the cA4 complex structure (color coded as in Fig. 1). c, Structural alignment of the SAVED domains of CALP/cA4 and Cap4/cA3 (white).
