Extended Data Fig. 8: RNA-seq analyses in sham conditions.
From: Dendritic cells direct circadian anti-tumour immune responses
(a-c) RNA-seq analyses of CD11c+ MHCIIhi cells in the dLN 24h after PBS injection (n = 3 mice) or after B16-F10-OVA cell (n = 5 mice) at ZT3, 9, 15 and ZT21 in WT mice, from 2 independent experiments. (a) Pathways found significantly enriched by over-representation analysis in the lists of significantly oscillating genes in PC1 (Reactome database) in WT mice. The same pathways from RNA-seq analyses in PBS injection mice were also plotted; n = 3 mice per timepoint. The vertical dashed line represents the significant P values, hypergeometric test. (b-c) Pathways found significantly enriched by over-representation analysis in the lists of significantly oscillating genes in PC1 and PC2 in PBS injection mice, hypergeometric test.
