Extended Data Fig. 1: Iteratively stimulated T cells populate non-lymphoid tissues.
From: Functional T cells are capable of supernumerary cell division and longevity
a) CD45.1+ 48° ISTC memory CD8 T cells were transferred to naïve mice, followed by three heterologous prime-boost-boost immunizations. Non-lymphoid tissues were analyzed 48 days after the 51° boost. Flow cytometry plots are gated on live CD8a+ lymphocytes that were not stained by intravascular in vivo antibody labeling. b) CD69 expression on endogenous 3° cells (CD45.1-) and 48° memory CD8 T cells (CD45.1+).Plots concatenated from four mice and experiment is representative of three similar experiments with similar results.
