Extended Data Fig. 6: Structural comparison between the active nc-Rag GTPases (RagAGTP-RagCGDP) and RagC in GTP-bound states, and between the nc-RagAGTP and RagA in GDP-bound states at the unique TFEB contact site.
From: Structure of the lysosomal mTORC1–TFEB–Rag–Ragulator megacomplex
a, Structures are superimposed based on the α8 of RagC. Structures of RagC in GTP-bound states are colored as gray, while the switch I regions are colored as pink. Residues 41–105 of TFEB are omitted. b, Structures are superimposed based on the α4 of RagA. Structures of RagA at GDP-bound states are colored in gray. The TFEB and nc-Rag GTPases are colored as in Fig. 1.
