Extended Data Fig. 9: Cryo-EM map of the active site of mTOR and overlapping between TFEB, S6K and PRAS40.
From: Structure of the lysosomal mTORC1–TFEB–Rag–Ragulator megacomplex
a, Cryo-EM map in the active site of mTOR is shown as transparent surface. The density is zoned within 3Å of the model. b, The cryo-EM density outside the zone range is shown as solid surface colored in gray. c-d, Superimposed structure of S6K (PDB: 5WBH) and PRAS40 (PDB: 5WBU) with mTORC1-TFEB-Rag-Ragulator based on the FRB domain of mTOR.
