Extended Data Fig. 1: Study cohort and cell lineage assignment. | Nature

Extended Data Fig. 1: Study cohort and cell lineage assignment.

From: Single-cell spatial immune landscapes of primary and metastatic brain tumours

Extended Data Fig. 1

a, Summary of patient samples. Patients underwent surgical resection and tumours were classified by a neuropathologist (M.C.G.). Gliomas were classified as: primary (first surgical resection), residual (second surgery to remove any remaining tumour), recurrent (surgical resection after tumour recurrence), or progression from grade II/III (resection of grade IV tumour that progressed from low grade glioma). Glioma samples were extracted from the tumour bulk or the tumour-adjacent normal. Brain metastasis samples were extracted from the tumour bulk (core) or the tumour/brain interface (margin). All clinical information was obtained from surgical and pathological reports. Number of cells acquired corresponds to the total number of cells segmented across all images. b, Schematic for cell lineage assignment strategy. Created with BioRender.com.

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