Extended Data Fig. 6: Comparison of burden versus common variant heritability explained by exome-wide significant genes.
From: Polygenic architecture of rare coding variation across 394,783 exomes
Each point represents a trait-gene significant burden association from the Genebass dataset. X axis values are the fraction of common variant heritability (estimated with HESS) explained by the LD-independent block containing that gene. Y axis values are the fraction of burden heritability (estimated with BHR) explained by the significant gene.
