Extended Data Fig. 2: Rv-1928z+41BBL and TRAC-1928z pre-infusion and in vivo CAR T cell phenotyping.
From: TET2 guards against unchecked BATF3-induced CAR T cell expansion
a,b, Pre-infusion transduction efficiency and phenotyping by flow cytometry of Rv-1928z+ 41BBL (a) and TRAC-1928z (b) CAR T cells. c,d, Tumour monitoring of NALM6 bearing mice treated with Rv-1928z+41BBL (c) and TRAC-1928z (d) CAR T cells. e,f, Differentiation phenotyping of pooled bone marrow CAR T cells at week 3 post infusion. Data from another experiment included in supplementary information. g, CAR T cell inhibitory receptor expression at week 3 post infusion from mouse bone marrow (n = 3). p values were determined by two-sided χ2 test (f). p < 0.05 was considered statistically significant. p values are denoted: p > 0.05, not significant, NS; *, p < 0.05. Replicate information for e,g are available in Supplementary Table 3.
