Extended Data Fig. 1: Schematic overview of mutations in Omicron S.
From: Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation
Top, amino acid changes in Omicron S compared to the SARS-CoV-2 Wuhan-Hu-1 isolate (NCBI accession number: NC_045512). Numbering is based on Wuhan-Hu-1 sequence. Mutations not reported in previous variants of concern are shown in red. NTD, N-terminal domain; RBD, receptor-binding domain; RBM, receptor-binding motif. Bottom, location of Omicron changes on the trimeric S protein. Domains are coloured similarly in both panels.
