Fig. 2: GMRs are associated with long-term substitution rates. | Nature

Fig. 2: GMRs are associated with long-term substitution rates.

From: Evolution of the germline mutation rate across vertebrates

Fig. 2: GMRs are associated with long-term substitution rates.

a,b, There is a positive association between the modelled yearly pedigree-based mutation rates and the macroevolutionary substitution rates when using phylogenetic regression (PGLS) on both UCEs and their flanking sequences (a) and whole-genome alignments (WGAs) (b). The grey dashed lines indicate equality. See Extended Data Fig. 5 for plots of the same data on a log scale and Extended Data Fig. 6 for a comparison of UCE and WGA methods.

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