Extended Data Fig. 7: Conserved amino acids selected for saturation mutagenesis.
From: Complete integration of carbene-transfer chemistry into biosynthesis

The residue labelled in blue is the haem ligand cysteine in those P450s. Residues labelled in red are two conserved residues previously reported to affect the catalytic behaviour in P450 BM3. Sequences were aligned with Clustal Omega64.