Extended Data Fig. 1: Correlation between simultaneously labelled ERMES components.
From: In situ architecture of the ER–mitochondria encounter structure
a: Fluorescence live cell microscopy of cells expressing Mdm34-eGFP and Mdm12-mCherry. Individual channels and merge are shown. b: Fluorescence live cell microscopy of cells expressing Mdm34-eGFP and Mmm1-mCherry. Individual channels and merge are shown. c: The fluorescence intensity of Mdm34-eGFP and Mdm12-mCherry, labelled in the same cells, correlates in puncta. n = 128 puncta, Pearson’s correlation R = 0.566, p = 3.38*10−12 (two-sided). d: The fluorescence intensity in a.u. of Mdm34-EGFP and Mmm1-mCherry, labelled in the same cells, correlates in puncta. n = 134 puncta, Pearson’s correlation R = 0.529, p = 5.18*10−11 (two-sided). Scale bars are 3 µm.
