Extended Data Fig. 1: Quality control in analyzing the scRNA-seq data.
From: Reply to: Ptbp1 deletion does not induce astrocyte-to-neuron conversion
a,b,c, Violin plots of n-count_RNA, n-feature_RNA and Percent_mt (mitochondrial transcripts) distribution in cells from WT, heterozygous or homozygous Ptbp1 KO cortex (a), striatum (b) and substantia nigra (c). Center lines in boxplots are the median and box is the interquartile range (IQR). n = 13198, n = 14732, n = 17071 cells for WT, heterozygous and homozygous Ptbp1 KO cortex; n = 12145, n = 12175, n = 15710 cells for WT, heterozygous and homozygous Ptbp1 KO striatum; n = 5741, n = 4518, n = 2965 cells for WT, heterozygous and homozygous Ptbp1 KO substantia nigra. d,e,f, Expression of cell type-specific marker genes in each cluster defined from cortex (d), striatum (e) and substantia nigra (f) scRNA-seq data.
