Extended Data Fig. 2: MP regulators inferred by SCENIC. | Nature

Extended Data Fig. 2: MP regulators inferred by SCENIC.

From: Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours

Extended Data Fig. 2

(a) Heatmap showing the mean correlations between regulon scores and MP scores (correlations were calculated separately within each sample, and then averaged across samples). Regulons were included if they had a consistent association with at least one MP, defined as correlation above 0.5 (or below −0.5) in at least 10 samples or in at least 30% of the samples with that MP (see Table S6 for a list of such regulons). (b) Distributions of the correlations whose means are shown in a for selected regulons associated with nine MPs (each shown in a separate panel). ex., extended.

Back to article page