Extended Data Fig. 6: Radial spoke 3 (RS3).
From: Axonemal structures reveal mechanoregulatory and disease mechanisms
a, Model and cryo-EM map showing the base of human RS3 and its association with IDAd/g. Coiled coils from CCDC96/113 and CFAP57 are docking factors for RS3. CFAP43/44 (components of the T/TH complex) are docking factors for IDAd/g. b, Model and cryo-EM map of C. reinhardtii RS3S. c, Domain organization of RS3S subunits. The boxes on FAP91 indicate consecutive binding sites for RS2, the N-DRC and RS3S. Both the oxidoreductase-like domain of FAP61 and the calmodulin (CaM)-like domain of FAP251 interact with FAP91. d, Atomic model of the docking factors for RS3S in C. reinhardtii.
