Extended Data Fig. 4: A link between NINJ1 and lower levels of serum AST and ALT in Genome-wide association studies (GWAS). | Nature

Extended Data Fig. 4: A link between NINJ1 and lower levels of serum AST and ALT in Genome-wide association studies (GWAS).

From: Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury

Extended Data Fig. 4: A link between NINJ1 and lower levels of serum AST and ALT in Genome-wide association studies (GWAS).

Regional plot of GWAS (UK Biobank random participants, n = 363, 228)15,42 showing correlation of a NINJ1 single nucleotide polymorphism (rs7018885, purple diamond in chromosome 9 locus) with lower serum AST (bottom) or ALT (top). P values were obtained from a two-sided test for the null hypothesis that the effect of genotype (at each single nucleotide polymorphism) on the ALT or AST values in a linear regression model was zero. P values are not adjusted for multiple tests across the genome.

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