Fig. 6: Translation efficiency of transcripts with allele-specific bias in RNA expression.
From: Single-cell quantification of ribosome occupancy in early mouse development
a, For each transcript, we aggregated RNA expression across replicates and phased SNPs to determine the ratio of reads supporting the paternal allele to the total. Genes are coloured by allelic bias in RNA expression in four-cell-stage (x axis) and eight-cell-stage (y axis) embryos. b, For the four-cell-stage and eight-cell-stage embryos, translation efficiency (that is, ribosome occupancy divided by RNA expression) of allele-biased and biallelic genes was compared using two-sided Wilcoxon rank sum tests. c, Translation efficiency of biallelic genes was compared with those that are monoallelically expressed (paternal ratio of 0 or 1). In the boxplots, the horizontal line corresponds to the median, the box represents the interquartile range and the whiskers extend to 1.5 times the interquartile range.
