Fig. 2: Development of oxygen tolerance in F. prausnitzii by stepwise adaptation.
From: Synergy and oxygen adaptation for development of next-generation probiotics

a, Oxygen tolerance of F. prausnitzii DSM 32186 in YCFAG medium after exposure to ambient air for 20 min compared with control plates incubated in anaerobiosis. b, Schematic presentation of the modified simulated human redox intestinal model (m-SHIRM) bioreactor. c, The oxidative adaptation strategy used to develop oxygen-tolerant strains of F. prausnitzii. d, Oxygen tolerance of the oxygen-adapted F. prausnitzii DSM 32379 developed from the parental strain DSM 32186. Oxygen exposure performed as in Fig. 2a. Numbers to the right of agar plates in a,d indicate dilution.