Extended Data Fig. 2: Kinetics of PR migration.
From: Neuronal migration prevents spatial competition in retinal morphogenesis
a, Trajectories of PR bidirectional migration from birth to final positioning relative to the apical surface (0 μm) shown as individual trajectories (n = 49 cells, N = 17 embryos) with superimposed mean trajectory ± s.d. b, Directionality ratio of PRs’ basal and apical migration shown as mean of all the tracks ± s.e.m. (n = 33 cells, N = 15 embryos). c,d, Basal (c) and apical (d) velocities (absolute mean velocities) of progenitors and PRs calculated from the trajectories shown in Fig. 1g–h. P value for comparison between cell types using Mann–Whitney test (two-sided): 0.0076 (c) and 0.0065 (d). The lower and upper hinges of the box indicate the 25th and 75th percentile, respectively; middle line indicates the median, whiskers indicate minimum and maximum. e,f, Density plot of absolute mean velocities (basal, e; apical, f) resampled with replacement 105 times for bootstrap estimation of differences (progenitor – PR): mean difference of −0.086 µm min−1 (e) and 0.17 µm min−1 (f).
